Fatty acid guide
Fatty acid

Omega-3

Omega-3 supplementation usually centers on EPA and DHA intake, with form, dose, and baseline diet shaping whether a given protocol is meaningful. Fish oil, algae oil, and krill oil differ more in sourcing and formulation than in the core fatty acids users are often targeting.

fish oil
epa dha
krill oil
algae omega-3

This guide covers all common forms and variations of omega-3 in one place. Use the sections below to find the form that fits your situation.

Body systems

Cardiovascular system
Inflammatory signaling
Neural membranes
Retinal tissue

Associated molecules

EPA
DHA
Triglycerides
Cell membrane phospholipids

Track it lightly

Omega-3 labels are messy. Track EPA and DHA separately in Micros Tracker so your experiment is based on actual fatty acid intake, not just 'fish oil' as a category.

Trying this? Start tracking it here.

Evidence snapshot

The most decision-relevant variable is usually combined EPA and DHA intake, not the marketing name on the front label.

Evidence is strongest in contexts like triglyceride lowering and correcting low intake, while broader wellness claims are often more diffuse.

Rancidity, underdosing, and label confusion are common practical problems.

Compound variations

Fish oil

Omega-3

The most common umbrella label, but actual EPA/DHA content varies widely.

Common use case

Users who tolerate marine oils and want the broadest product selection.

Dosage note

Compare labels by EPA and DHA, not capsule count.

Krill oil

Omega-3

Usually lower-dose per capsule and often marketed around phospholipid delivery.

Common use case

Users who specifically prefer krill-based products.

Dosage note

The evidence edge over standard fish oil is not established.

Algae omega-3

Omega-3

A non-fish source of DHA and sometimes EPA.

Common use case

Users who avoid fish-derived products.

Dosage note

Check whether EPA is included because some formulas skew heavily toward DHA.

Dosage and best practices

Dosage principles

  • Look for actual EPA and DHA amounts per serving, not just total fish oil.
  • Take with food when tolerance or absorption is an issue.
  • Reassess whether the dose matches the goal: general intake support is different from targeted triglyceride protocols.

Best practices

  • Choose products that clearly disclose EPA and DHA.
  • Track bruising, reflux, and GI tolerance if you increase dose.
  • Account for fish intake before assuming you need a high-dose product.

Literature and references